<b>Possible Pathophysiological Mechanism for C</b><b>hilblains</b>

An alternative pathophysiological mechanism for unstable angina.

[The mechanism of phonation; its pathophysiological aspects].

The phonatory function of the larynx and its disturbance were discussed on the basis of the author's data of 1) electromyographical observation of the human larynx, 2) radiographical study of the larynx, 3) measurement of the mean subglottal air pressure as well as the vibratory subglottal pressure variation during phonation, and 4) analysis of vocal cord movements during phonation with high sp...

Oral Hypoglycemic Drugs: Pathophysiological Basis of Their Mechanism of Action

Type 2 diabetes is a syndrome characterized by relative insulin deficiency, insulin resistance and increased hepatic glucose output. Medications used to treat the disease are designed to correct one or more of these metabolic abnormalities. Current recommendations of the American Diabetes Association (ADA) and European Association for the Study of Diabetes (EASD) include diet and exercise as fi...

The pathophysiological mechanism underlying Brugada syndrome: depolarization versus repolarization.

This Point/Counterpoint presents a scholarly debate of the mechanisms underlying the electrocardiographic and arrhythmic manifestations of Brugada syndrome (BrS), exploring in detail the available evidence in support of the repolarization vs. depolarization hypothesis.

A Novel Pathophysiological Mechanism Contributing to Trigeminal Neuralgia.

Trigeminal neuralgia (TN) is a form of neuropathic pain that affects the fifth cranial nerve, the most widely distributed nerve in the head. Although TN has been associated with a variety of pathological conditions, neurovascular compression on the trigeminal nerve, as it exits the brain stem, is the most frequent reported cause. This compression provides a progressive demyelination of the nerv...